The Virginia Tech Alpha Pi Mu Chapter has been among the most active in the nation, winning national awards on several occasions including the Outstanding Chapter Award for the 2007-2008 academic year. The chapter carries on numerous activities designed to support the ISE Department, the College of Engineering, and the University.

Activities include the following:

• Volunteering at premier events such as the Committee of 100 Casino Night
• Coordinating and helping out with Casino Night with IIE
• Volunteering at the local animal shelter and for the YMCA
• Helping out at the ISE annual Town Hall Meetings
• Helping out at the ISE Spring Fling
• Hosting various social events for faculty and students including the French Design Team social
• Sponsoring various companies with information sessions and other various events such as the Deloitte Donut Day
• Hosting various information sessions and panels about career and internship opportunities
• Inviting various speakers including alumni to speak about their work-related experience
• Taking part of Virginia Tech's annual Big Event
• Presenting at various engineering showcases such as the Freshmen Engineering Major Mixer